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Avanscure Lifesciences Pvt. Ltd., global Manufacturer of Theophylline SR Pellets 50%,60% offers for your requirements of RND / Development quantities or commercials, based on status of the product.
Pellet can be used to formulate tablets, capsules, and caplets that deliver single active compounds, as well as multiple active compounds, each requiring different release patterns, within a single dosage form. Our pellets containing appropriate active in percentage can be used to fill different strengths dosage form ,thus avoiding repetitious & costly strength specific validations Pellets filled in transparent capsules.
Theophylline, also known as dimethylxanthine, is used in therapy for respiratory diseases such as COPD and asthma under a variety of brand names. Because of its numerous side-effects, the drug is now rarely administered for clinical use.
It is naturally found in tea, although in trace amounts (~1 mg/L), significantly less than therapeutic doses. It is found also in cocoa beans. Amounts as high as 3.7 mg/g have been reported in Criollo cocoa beans.
The main actions of theophylline involve:
Relaxing bronchial smooth muscle
Increasing heart muscle contractility and efficiency; as a positive inotropic
Increasing heart rate: positive chronotropic
Increasing blood pressure
Increasing renal blood flow
Some anti-inflammatory effects
Central nervous system stimulatory effect mainly on the medullary respiratory center.
Theophylline SR Pellets